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Tuesday, November 27, 2012

Prevent weight gain with red wine - by Emily Main



Prevent weight gain with red wine


As if you needed another reason to enjoy a good glass of red wine! Researchers from Purdue University have found that a compound called piceatannol found in red wine prevents or delays immature fat cells from developing into mature fat cells. Not a drinker? The same compound exists in the seeds and skin of red grapes and blueberries.
Ok so being who I am which is someone who feels a certain responsibility to readers and sharing all of the knowledge I gain from articles, research, etc.  I felt that it was my duty to do some digging piceatannol.  I'm not sure if it necessarily prevents weight gain but according to Pub med it has some serious agents that prevents other things.  I'm all about drinking the red wine.  I mean who could argue with all of these medical benefits. ;o)


Piceatannol (3, 3', 4, 5'-trans-trihydroxystilbene), a naturally occurring hydroxylated analogue of resveratrol, is less studied than resveratrol but displays a wide spectrum of biological activity. Piceatannol has been found in various plants, including grapes, passion fruit, white tea, and Japanese knotweed. Besides antioxidative effects, piceatannol exhibits potential anticancer properties as suggested by its ability to suppress proliferation of a wide variety of tumor cells, including leukemia, lymphoma; cancers of the breast, prostate, colon and melanoma. The growth-inhibitory and proapoptotic effects of piceatannol are mediated through cell-cycle arrest; upregulation of Bid, Bax. Bik, Bok, Fas: P21(WAF1) down-regulation of Bcl-xL; BCL-2, clAP, activation of caspases (-3, -7,- 8, -9), loss of mitochondrial potential, and release of cytochrome c. Piceatannol has been shown to suppress the activation of some transcription factors, including NF-kappaB, which plays a central role as a transcriptional regulator in response to cellular stress caused by free radicals, ultraviolet irradiation, cytokines, or microbial antigens.

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